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Alpha-2 receptor agonist drugs such as xylazine, romifidine, detomidine, and medetomidine, are used frequently in veterinary species (particularly large animal), but are rarely used in people.

Guaifenesin is used as a muscle relaxant prior to anesthesia induction in some animals.

To become an ACVAA board-certified Diplomate, veterinarians must have at least one year of clinical practice experience followed by three years of anesthesia residency training under the supervision of ACVAA Diplomates, have accepted for publication a scientific peer-reviewed research article, and passed both a written and oral examination.

In Europe, the European College of Veterinary Anaesthesia and Analgesia (ECVAA) is one of 23 specialty organizations recognized by the European Board of Veterinary Specialisation.

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Aggressive animals may require anesthesia in order to handle and perform a physical exam or obtain blood for testing.Anesthesia is required for many surgical procedures which require the patient to be immobile, unaware, and without pain.Furthermore, anesthesia aims to minimize the surgical stress response.The Academy of Veterinary Technician Anesthetists is a provisional specialty academy of the North American Veterinary Technician Association and is responsible for licensing technicians as being specialized in anesthesia.

For a technician to become specialized, they must be a licensed technician in their state, accumulate 6000 hours of work in veterinary medicine (at least 75% of which must be in anesthesia), 40 hours of continuing education related to anesthesia, demonstrate proficiency in anesthesia skills, and pass a comprehensive written examination.Horses, due to their complex physiology as performance animals, suffer a number of difficulties that can complicate anesthesia.

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