They all have significant side effects and some are used off-label, meaning they were tested and approved for a condition other than anxiety or were designed for another species.
Many horse owners turn to calming supplements to quiet their hose.
Minor tranquilizers are more frequently used to combat anxiety.
Examples of minor tranquilizers include diazepam (Valium), which is used frequently in foals to facilitate veterinary procedures, and alprazolam (Xanax), which is used anecdotally and infrequently in horses for anxiety.
There are two categories of tranquilizers: major and minor.
Major tranquilizers induce relaxation and are antipsychotic medications; in humans they are used for major mental illnesses.
Horses that have been administered sedatives are typically unaware of their surroundings, but sedatives will not prevent all equine reactions, like kicking and biting—they may actually even increase this risk.
These include xylazine (Rompun), detomidine (Dormosedan) and romifidine (Sedi Vet).
Common sedatives include xylazine (Rompun), detomidine (Dormosedan) and romifidine (Sedi Vet).